Противоглистные средства

Противоглистные средства -    |                          | |---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------| | Фенасал,              | Парализует нервно-       | Тениаринхоз,            | После                   | Не установлены  | Не установлены   | Порошок.           | | Phenasalum;         | мышечную систему и    | дифиллоботриоз,      | соответствующей  |                          |                             | Хранение:         | | синоним:              | разрушает покровные    | гимеволепидоз          | подготовки            |                           |                             | список Б; в        | | йомезан,              | ткани плоских червей    |                                  | (диета,                  |                           |                             | сухом месте      | | никлосамид и др.  |                                     |                                  | слабительное)       |                           |                             |                          | |                             |                                      |                                  | внуть однократно  |                           |                             |                          | |                             |                                      |                                  | взрослым 2 г;        |                           |                             |                          | |                             |                                      |                                  | детям до 3 лет      |                           |                             |                          | |                             |                                      |                                  | 0,5 г, 3—6 лет 1 г, |                           |                             |                          | |                             |                                      |                                  | 6—9 лет 1,5 г,       |                           |                             |                          | |                             |                                      |                                  | старше 9 лет 2 г.   |                           |                             |                          | |                             |                                      |                                  | За 15 мин до         |                           |                             |                          | |                             |                                      |                                  | приема фенасала  |                           |                             |                          | |                             |                                      |                                  | дают 1—2 г           |                           |                             |                          | |                             |                                      |                                  | натрия                  |                           |                             |                          | |                             |                                      |                                  | гидрокарбоната.    |                           |                             |                          | |                             |                                      |                                  | При                       |                           |                             |                          | |                             |                                      |                                  | гименолепидозе    |                           |                             |                          | |                             |                                      |                                  | лечение                |                           |                             |                          | |                             |                                      |                                  | фенасалом           |                           |                             |                          | |                             |                                      |                                  | состоит из 3          |                           |                             |                          | |                             |                                      |                                  | семидневных        |                           |                             |                          | |                             |                                      |                                  | циклов с                |                           |                             |                          | |                             |                                      |                                  | интервалами 7      |                           |                             |                          | |                             |                                      |                                  | дней                     |                           |                             |                          | |---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------| | Хлоксил,              | Вызывает деструкцию   | Описторхоз,              | Внутрь взрослым  | Головная боль,   | Заболевания         | Порошок.           | | Chloxylum             | нуклеопротеидов в        | клонорхоз,                | в суточной дозе    | чувство легкого  | печени и сердца,  | Хранение:          | |                             | клетках кишечного        | фасциолез                | из расчета по        | опьянения, боли | беременность       | список Б           | |                             | эпителия и паренхимы  |                                  | 0,15 г/кг в течение | в области           |                             |                          | |                             | трематод и угнетает      |                                  | 2 дней; по 0,1 г/кг  | печени,              |                             |                          | |                             | углеводный обмен         |                                  | в течение 3 дней   | аллергические    |                             |                          | |                             |                                      |                                  | или по 0,06 г/кг в   | реакции              |                             |                          | |                             |                                      |                                  | течение 5 дней.     |                           |                             |                          | |                             |                                      |                                  | Суточную дозу      |                           |                             |                          | |                             |                                      |                                  | принимают по 2 г  |                           |                             |                          | |                             |                                      |                                  | каждые 10 мин.     |                           |                             |                          | |                             |                                      |                                  | Через 2 ч после    |                           |                             |                          | |                             |                                      |                                  | приема хлоксила   |                           |                             |                          | |                             |                                      |                                  | дают                     |                           |                             |                          | |                             |                                      |                                  | желчегонные         |                           |                             |                          | |                             |                                      |                                  | средства и 1—2    |                           |                             |                          | |                             |                                      |                                  | раза в неделю       |                           |                             |                          | |                             |                                      |                                  | проводят               |                           |                             |                          | |                             |                                      |                                  | дуоденальное       |                           |                             |                          | |                             |                                      |                                  | зондирование (в    |                           |                             |                          | |                             |                                      |                                  | течение 1 мес.)     |                           |                             |                          | |---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------| | Экстракт              | Парализует нервно-       | Тениидозы,               | Внутрь после        | Тошнота, рвота,  | Сердечная           | В склянках и в   | | мужского              | мышечную систему       | дифиллоботриоз,      | соответствующей  | понос,                | недостаточность,  | капсулах по       | | папоротника         | плоских червей,            | гименолепидоз          | подготовки            | головокружение, | болезни печени и  | 0,5 г. Хранение: | | густой, Extractum | разобщает процессы     |                                  | (диета, солевое     | головная боль,   | почек, язвенная    | список Б. в        | | Filicis maris          | окислительного             |                                  | слабительное        | иногда                | болезнь, острые    | плотно               | | spissum                | фосфорилирования       |                                  | однократно при     | судорога,           | заболевания         | укупоренных     | |                             |                                      |                                  | тениидозах и         | угнетение           | желудочно-           | склянках в         | |                             |                                      |                                  | дифиллоботриозе) | дыхания,            | кишечного тракта, | защищенном от | |                             |                                      |                                  | взрослым 4—7 г    | коллапс,             | беременность,      | света месте      | |                             |                                      |                                  | (по 0,5 г каждые    | атрофия             | резкое                  |                          | |                             |                                      |                                  | 3 мин); детям 2     | зрительного        | истощение,           |                          | |                             |                                      |                                  | лет 1 г, 3 лет 1,5   | нерва,                | анемия,                |                          | |                             |                                      |                                  | г, 4 лет 2 г, 5—6    | дистрофические | туберкулез            |                          | |                             |                                      |                                  | лет 2—2,5 г, 7—9  | изменения          |                             |                          | |                             |                                      |                                  | лет 3—3,5 г, 10—  | печени               |                             |                          | |                             |                                      |                                  | 12 лет 3,5 г, 13—   |                           |                             |                          | |                             |                                      |                                  | 16 лет 4 г. Детям   |                           |                             |                          | |                             |                                      |                                  | до 2 лет препарат  |                          |                             |                          | |                             |                                      |                                  | не назначают.       |                           |                             |                          | |                             |                                      |                                  | Через 1—2 ч         |                           |                             |                          | |                             |                                      |                                  | дают солевое        |                           |                             |                          | |                             |                                      |                                  | слабительное.       |                           |                             |                          | |                             |                                      |                                  | При                       |                           |                             |                          | |                             |                                      |                                  | гименолепидозе    |                           |                             |                          | |                             |                                      |                                  | препарат               |                           |                             |                          | |                             |                                      |                                  | назначают             |                           |                             |                          | |                             |                                      |                                  | однократно в         |                           |                             |                          | |                             |                                      |                                  | следующих           |                           |                             |                          | |                             |                                      |                                  | дозах: детям 2      |                           |                             |                          | |                             |                                      |                                  | лет 0,2 г, 3—4 лет |                           |                             |                          | |                             |                                      |                                  | 0,3 г, 5—6 лет 0,5  |                           |                             |                          | |                             |                                      |                                  | г, 7—8 лет 0,6 г,    |                           |                             |                          | |                             |                                      |                                  | 9—10 лет 0,7 г,     |                           |                             |                          | |                             |                                      |                                  | 11—12 лет 0,9 г,    |                           |                             |                          | |                             |                                      |                                  | 13—14 лет 1 г, 15  |                           |                             |                          | |                             |                                      |                                  | лет и старше 1,5   |                           |                             |                          | |                             |                                      |                                  | г. В указанных      |                           |                             |                          | |                             |                                      |                                  | дозах лечение       |                           |                             |                          | |                             |                                      |                                  | препаратом           |                           |                             |                          | |                             |                                      |                                  | проводят тремя     |                           |                             |                          | |                             |                                      |                                  | однодневными      |                           |                             |                          | |                             |                                      |                                  | циклами с             |                           |                             |                          | |                             |                                      |                                  | перерывами          |                           |                             |                          | |                             |                                      |                                  | между ними 7       |                           |                             |                          | |                             |                                      |                                  | дней. Высшая       |                           |                             |                          | |                             |                                      |                                  | разовая доза для  |                           |                             |                          | |                             |                                      |                                  | взрослых внутрь   |                           |                             |                          | |                             |                                      |                                  | 8 г (однократно)    |                           |                             |                          | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Библиогр.: Лекарственные препараты, применяемые при паразитарных заболеваниях, под ред. А.И. Кротова, с. 85, М., 1979; Озерецковская Н.Н., Зальнова Н.С. и Тумольская Н.И. Клиника и лечение гельминтозов. Л., 1985; Озерецковская Н.Н. и др. Новый отечественный антигельминтик медамин, Мед. паразитол., № 5, с. 7, 1986. II Противоглистные средства (antihelminthica; син.: антигельминтики, антигельминтные средства) лекарственные средства, применяемые для лечения глистных инвазий человека и животных (пиперазин, экстракт мужского папоротника, хлоксил и др.).